Filtering operation using silicone implant was performed on 20 Albino Rabbits´ eyes. [-shaped silicone pieces were used as implant in this experiment to prevent adhesion between subconjunctival tissue and sclera.
During the experimeptal course, intraocular pressure, subconjunctival bleb,. existance of silicone piece- and of scleral gap and state of conjunctiva over the silicone piece were observed and ,at the end of the experiment, histopathologic examination was performed.
Conjunctival tear was observed over one half of eyes experimented and subconjunctival bleb was not present at all in all cases.
The lowering of the intraocular pressure after operation was not significant. Scleral gap was
occluded completely or partially by fibrosis and inflammatory cells except 2 eyes.
After 5?6 weeks´ observation, silicone pieces were remained on position in 5 eyes out of 6. Histopathologically, I observed fibrosis, chronic inflammatory cells and occasionally granulom atous change of foreign body type near the silicone piece.
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